Supply Chain

NDA consultants have helped Pharmaceutical companies ensure the supply of products with annual sales up to $5bn.
We help companies resolve supply chain issues and ensure continuity of supply.

With our network of Consultants, Strategic Partners and Associates we are able to quickly identify supply chain issues and implement solutions that work, whether it is the resolution of manufacturing process issues or establishing proven supply chain management business solutions.

We have helped clients establish supply chains for all major dosage forms including novel drug loaded devices.

We do this by helping you:

NDA can help you establish new and alternative supply chains to maximize cost advantages and ensure continuity of supply.

SUPPLY CHAIN CASE STUDY – Alternative Supply Routes 

ISSUE:

A pharmaceutical company was unable to meet demand for a major product because of technical issues at a supply site resulting in the potential loss of $250millon in sales.

OBJECTIVE:

Quickly implement measures to mitigate loss in sales and establish alternative supply routes.

DELIVERABLE:

Developed and implemented a global rationing process to ensure that the limited supply of product was used to meet the needs of major / priority customers.

Established a multifunctional technical team and using BRITEST© methodology identified the technical issues preventing supply. The technical team then implemented a plan of work to quickly resolve the process issues.
Identified alternative manufacturing facilities and established plans to start-up manufacturing at alternative manufactures as quickly as possible.

Supported the technical transfer of production to alternative manufacturing facilities and the preparation of stability data to support regulatory approval.

Worked with regulatory affairs experts to establish and implement a plan to gain regulatory approval for new facilities as quickly as possible.

Executed strategies which delivered results in record time, resolved back order problems, and created the framework for product growth.

SUPPLY CHAIN CASE STUDY – Simplification

ISSUE:

Generic competition was eroding volumes and margins on an end-of-life-cycle product. The supply chain, which crossed three continents, had to become more cost-effective and flexible

OBJECTIVE:

Simplify the supply chain, driving cost reductions whilst maintaining required standards of quality and service.

DELIVERABLE:

A decision had been made to close one production site and transfer supply of the main active to a low-cost source.
An international and multi-functional team was established to:

• Identify and validate the new source of active materiel
• Plan and implement inter-site product transfers
• Sourcing options were identified and product from each of the potential suppliers tested through the supply chain. A preferred supplier was selected.

Products were progressively transferred taking full account of regulatory requirements and expectations of customers and other stakeholders.

All activities were completed in the required 24 month timescales.

SUPPLY CHAIN CASE STUDY – Distribution Optimization

ISSUE:

A year after a major pharmaceutical merger, each company was still shipping independently to North Africa from its European sites.

OBJECTIVE:

Define and implement a common solution for distribution to North Africa, taking cost and time out of the network.

DELIVERABLE:

A study was carried out to calibrate existing and future requirements.

Internal and external options were developed. Quality and service were the key criteria, another  major driver being the capability of the different solutions to cater for evolving requirements.

A third-party solution was agreed as the preferred solution after the development of an invitation to tender and an analysis of the proposals received.

A transition plan was developed and implemented along agreed timescales, with no adverse impact on quality or service.

40% was taken out of the total cost of distribution to North Africa.